Hcv inhibiting bi-cyclic pyrimidines

Details Hcv inhibiting bi-cyclic pyrimidines Hcv inhibiting bi-cyclic pyrimidines

A - Human Necessities

61

K

A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/52 (2006.01) A61K 31/53 (2006.01) A61K 31/5377 (2006.01) A61P 1/16 (2006.01) A61P 31/14 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2577745

The present invention relates to the use of bi-cyclic pyrimidines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections. In addition, the present invention relates to processes for preparation of such pharmaceutical compositions. The present invention also concerns combinat ions of the present bi-cyclic pyrimidines with other anti-HCV agents.

L'invention concerne l'utilisation de pyrimidines bicycliques comme inhibiteurs de réplication du VHC ainsi que leur utilisation dans des compositions pharmaceutiques susceptibles de traiter ou de combattre des infections par le VHC. L'invention concerne également des procédés permettant de préparer ces compositions pharmaceutiques. L'invention concerne enfin des combinaisons des pyrimidines bi-cycliques précitées avec d'autres agents anti-VHC.

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