Methods and compositions for treating wounds

A - Human Necessities – 61 – K

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A61K 31/715 (2006.01) A61L 26/00 (2006.01)

Patent

CA 2154124

Wound treatment compositions include an oxidized cross-linked polysaccharide which has a chemically induced charge. Preferred polysaccharides are cross-linked dextrans. A charge is preferably provided by diethylaminoethyl groups (DEAE groups) or carboxymethyl groups. The oxidized cross-linked polysaccharide can be applied as a powder directly to a wound site. Alternatively, the oxidized cross-linked polysaccharide can be combined with a delivery vehicle to form a liquid or past to be applied to a wound site.

Des compositions de traitement des blessures comprennent un polysaccharide réticulé oxydé qui a une charge induite chimiquement. Les polysaccharides préférés sont des dextranes réticulés. Une charge est fournie de préférence par des groupes de diéthylaminoéthyle (groupes DEAE) ou des groupes de carboxyméthyle. Le polysaccharide réticulé oxydé peut être appliqué sous forme d'une poudre directement à un site de plaie. Dans un autre mode de réalisation, le polysaccharide réticulé oxydé peut être combiné avec un véhicule d'administration pour former un liquide ou appliqué à un site de blessure.

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