Potentiation of therapeutic effects of fatty acids

A - Human Necessities – 61 – K

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A61K 31/20 (2006.01) A61K 31/19 (2006.01) A61K 31/405 (2006.01) A61K 31/415 (2006.01) A61P 19/02 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2446363

The oral administration of an essential fatty acid, preferably eicosapentaenoic acid, at a defined purity together with an inhibitor of COX-1 or COX-2 or LOX or one or more of the FACL enzymes gives improved therapeutic results over administrationof the fatty acid alone.

Selon l'invention, l'administration orale d'un acide gras essentiel, de préférence un acide eicosapentaénoïque, à un degré de pureté définie, conjointement avec un inhibiteur de COX-1 ou de COX-2 ou de LOX ou d'un ou plusieurs des enzymes FACL, produit des résultats thérapeutiques meilleurs que ceux obtenus par l'administration du seul acide gras.

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