Methods and kits for diagnosing tumorigenicity

Details Methods and kits for diagnosing tumorigenicity Methods and kits for diagnosing tumorigenicity

C - Chemistry, Metallurgy

07

K

C07K 16/22 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/00 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/563 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2504178

Methods and kits for diagnosing tumorigenicity by measuring the concentration of GP88 in blood, plasma, serum, saliva, urine and other biological fluids. The methods and kits detect GP88 in biological fluids at a concentration as low as about 0.1 to 10 nanograms per milliliter and are useful for determining whether a patient has a tumorigenic condition, whether the patient is likely to be responsive to anti-tumorigenic therapies, and whether the treated patient is responding to anti-tumorigenic therapy by measuring the concentration of GP88 in the patient's serum or other biological fluid.

La présente invention concerne des procédés et des trousses pour diagnostiquer une cancérogénicité par mesure de la concentration en GP88 dans du sang, du plasma, du sérum, de la salive, de l'urine et d'autres fluides biologiques. Ces procédés et trousses permettent de détecter GP88 dans des fluides biologiques à une concentration allant d'environ 0,1 à 1 nanogrammes par millilitre et sont utilisés pour déterminer si un patient présente une pathologie cancérigène, s'il est susceptible de réagir à des traitements anticancéreux et si le patient traité réagit à un traitement anticancéreux en mesurant la concentration en GP88 dans du sérum ou un autre fluide biologique du patient.

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