Purine derivatives and their use for treatment of autoimmune...

Details Purine derivatives and their use for treatment of autoimmune... Purine derivatives and their use for treatment of autoimmune...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/52 (2006.01)

Patent

CA 2608314

Compounds useful in the treatment of autoimmune disease are described by the following general formula (I): n = 0-2 m = 0-2 m is not necessarily equal to n; where R1, R3 = NH2, F, Cl, C1-C4 alkoxy or phenoxy group, but R1 is not necessarily equal to R3; and R2 = H, F, Cl, NH2, or NH- R- XH; where R = - (CH2)p - p = 2-4 = Formula (II), Formula (III) = Formula (IV) q = 0-3 X = CH2, NH, O, or S.

La présente invention concerne décomposée qui convienne pour le traitement de maladie auto-immune, représenté par la formule générale (I) suivante : n = 0-2 m = 0-2 m n'étant pas nécessairement égal à n; dans cette formule R1, R3 = NH2, F, Cl, C1-C4 alcoxy ou un groupe phénoxy, mais R1 n'est pas nécessairement égal à R3; et R2 = H, F, Cl, NH2, ou NH- R- XH; avec R = - (CH2)p - p = 2-4 = Formule (II), Formule (III) = Formule (IV) q = 0-3 X = CH2, NH, O, ou S.

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