Mucosal or enteral administration of biologically active...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/82 (2006.01)

Patent

CA 2615218

A method of systemically delivering a biologically active, recombinant biomolecule, in a biologically active form, to a subject in need thereof, the method comprising, enterally or mucosally administering to the subject a therapeutically effective amount of plant cells expressing an exogenous biologically active recombinant biomolecule, thereby systemically delivering the biologically active recombinant biomolecule, in a biologically active form, to the subject.

Cette invention concerne une méthode d'administration systémique d'une biomolécule recombinante biologiquement active, dans une forme biologiquement active, à un sujet nécessitant un tel traitement, laquelle méthode consiste à administrer au sujet par voie entérale ou mucosale une quantité thérapeutiquement efficace de cellules végétales exprimant une biomolécule recombinante biologiquement active exogène, ce qui permet d'administrer au sujet de manière systémique la biomolécule de recombinaison biologiquement active, dans une forme biologiquement active.

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