Pharmaceutical formulations containing quetiapine

Details Pharmaceutical formulations containing quetiapine Pharmaceutical formulations containing quetiapine

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/48 (2006.01) A61K 9/50 (2006.01) A61K 31/554 (2006.01)

Patent

CA 2542836

The invention provides novel dosage forms of quetiapine and its salts, particularly quetiapine hemifumarate including wax dosage forms, press-coat dosage forms, and sprinkle dosage forms, and other novel dosage forms. The invention also provides sustained release and pulsed release dosage forms of quetiapine and its salts. Methods of making novel quetiapine dosage forms are given. Use of said compositions for the manufacture of medicaments for treating shizophenia and other neuropsychiatric disorders by administering an effective amount of the dosage forms disclosed herein, either alone or in combination with one or more other medicaments, are also provided by the invention.

L'invention concerne de nouvelles formes dosifiées de quétiapine et de ses sels, notamment, l'hémifumarate de quétiapine contenant des formes dosifiées cirées, des formes dosifiées doubles, et des formes dosifiées à saupoudrer, et d'autres nouvelles formes dosifiées. Ladite invention a aussi trait aux formes dosifiées à libération pulsée et à libération soutenue de quétiapine et de ses sels, ainsi qu'à des méthodes d'élaboration de nouvelles formes dosifiées de quétiapine. Cette invention a également pour objet l'utilisation de ces compositions dans la fabrication de médicaments destinés au traitement de la schizophrénie et d'autres troubles neuropsychiatriques par administration d'une quantité efficace des formes dosifiées susmentionnées, seules ou en combinaison avec au moins un autre médicament.

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