Polymeric short interfering rna conjugates

Details Polymeric short interfering rna conjugates Polymeric short interfering rna conjugates

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07H 21/02 (2006.01) C08G 65/329 (2006.01) C12N 15/63 (2006.01) A61K 48/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2664271

The present invention provides polymeric siRNA conjugates. Methods for down-regulation of gene expression in vivo and in vitro and for inhibition of the growth of cancer cells using the conjugates are also disclosed.

La présente invention concerne des conjugués d'ARNsi polymères. Des procédés pour la régulation à la baisse de l'expression génique in vivo et in vitro et pour l'inhibition de la croissance des cellules cancéreuses utilisant les conjugués sont également révélés.

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