A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/74 (2006.01) A61K 9/00 (2006.01) A61K 9/02 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01)
Patent
CA 2176474
A vaginal suppository or other type of vaginal passary such as cream, foam or ointment, which contains as its active ingredients at least one pharmaceutically acceptable, topically safe antimicrobial agent, such as an agent selected from the group of benzalkonium chloride, cetylpyridinium chloride, chlorhexidine gluconate and povidone iodine, imidiazolidinyl urea and diazolidinyl urea and a viable colony of micro-encapsulated lactobacilli bacteria. The viable lactobacilli are included in the suppository in micro encapsulated form, which protects the bacteria during storage of the suppository from the action of the bacteriocidal agent. When exposed to the vaginal milieu the micro encapsulation breaks down sufficiently to release the lactobacilli bacteria. The lactobacilli bacteria serve to maintain or re-establish a healthy lactobacilli based flora on the vaginal wall, and excrete hydrogen peroxide and other bactericidins which suppress abnormal flora conditions that promote infections,
Suppositoires vaginaux ou tout autre type des pessaires vaginaux de type crème, mousse ou onguent contenant comme principes actifs au moins un agent antimicrobien pharmacocompatible et topiquement sûr, tel qu'un agent sélectionné parmi le chlorure de benzalconium, le chlorure de cétylpyridinium, le gluconate de chlorhexidine, l'iode povidone, l'imidiazolidinyle urée, la diazolidinyle urée ainsi qu'une colonie viable de lactobacilles microencapsulés. Les lactobacilles viables sont présents dans le suppositoire sous une forme microencapsulée qui pendant le stockage les protège de l'action de l'agent bactéricide. Une fois dans le milieu vaginal, le microencapsulage se rompt suffisamment pour libérer les lactobacilles. Ces derniers servent à maintenir ou reconstituer une flore lactobacillaire saine et excrètent du peroxyde d'hydrogène et autres bactéricidines qui combattent les états anormaux de la flore responsables d'infections.
Gowling Lafleur Henderson Llp
Lafor Laboratories Limited
LandOfFree
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