Human proteins stam2a and stam2b and cdnas encoding these...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2347409

Human proteins STAM2a and STAM2b respectively containing the amino acid sequences of SEQ ID NOS: 1 and 2 which are novel signal transducers interacting with a cytokine signal transducer AMSH; cDNAs respectively containing the base sequences of SEQ ID NOS: 3 and 4 which are human genes encoding these proteins; and antibodies against the proteins STAM2a and STAM2b.

Cette invention se rapporte à des protéines humaines STAM2a et STAM2b contenant respectivement des séquences d'acides aminés ayant les numéros d'identification de séquence 1 et 2, qui constituent de nouveaux transducteurs de signal entrant en interaction avec un transducteur de signal cytokine AMSH; à des ADNc contenant respectivement les séquences de base ayant les numéros d'identification de séquence 3 et 4, qui sont des gènes humains codant ces protéines; et à des anticorps contre ces protéines STAM2a et STAM2b.

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