Process for the preparation of...

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C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A01N 43/90 (2006.01) C07D 239/00 (2006.01) C07D 249/00 (2006.01)

Patent

CA 2423479

2-Akoxy-6-trifluoromethyl-N-(1,2,4]triazolo[1,5-c]pyrimidin-2- yl]benzenesulfonamides are prepared by introducing the 2-alkoxy substituent of the benzenesulfonamide ring in the last step by contacting the corresponding 2- fluoro substituted material with the appropriate alkoxide.

Pour la préparation de 2-akoxy-6-trifluorométhyl-<i>N 1,2,4]triazolo[1,5-c]pyrimidin-2-yl]benzènesulfonamides, on introduit le substituant 2-alkoxy du noyau de benzènesulfonamide au cours de la dernière opération. A cette fin, on met le matériau substitué 2-fluoro correspondant en contact avec l'alkoxyde approprié.

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