A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/24 (2006.01) A61K 9/107 (2006.01) A61K 9/127 (2006.01) A61K 31/167 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 31/405 (2006.01) A61K 31/60 (2006.01) A61K 31/616 (2006.01) A61K 31/66 (2006.01) A61K 47/48 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2431606
A novel pharmaceutical composition is provided by which nonsteroidal anti- inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulstion for internal, oral, direct or topical administration.
L'invention concerne une composition pharmaceutique dans laquelle des anti-inflammatoires non stéroïdes sont ajoutés directement à une huile à base de phospholipide, comme les huiles de lécithine, ou qui sont ajoutés directement à une huile biocompatible ayant reçu un phospholipide, donnant une formulation à base d'anti-inflammatoires non stéroïdes qui a une faible toxicité vis-à-vis du tractus gastro-intestinal et un effet thérapeutique amélioré pour le traitement ou la prévention de l'inflammation, de la douleur, de la fièvre, de l'agrégation plaquettaire, des ulcérations tissulaires et/ou autres troubles propres aux tissus. Il s'agit d'une composition pouvant se présenter sous diverses formes: solution non aqueuse, pâte, suspension, dispersion, suspension colloïdale ou bien encore émulsion ou microémulsion aqueuse, pour administration interne, orale ou topique.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Board Of Regents Of The University Of Texas System
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