Desferrithiocin analogue actinide decorporation agents

A - Human Necessities – 61 – K

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Details

A61K 31/426 (2006.01) A61P 39/04 (2006.01) C07D 277/10 (2006.01)

Patent

CA 2684837

A pharmaceutical composition comprising a non-toxic effective amount of an actinide decorporation agent and a pharmaceutically acceptable carrier therefore, the actinide decorporation agent comprising a hexacoordinate desferrithiocin analogue capable of chelating an actinide in vivo and a method for removing an actinide from the tissue of a human or nonhuman mammal.

La présente invention concerne une composition pharmaceutique comprenant une quantité effective non toxique d'un agent de décorporation de l'actinide et d'un support pharmaceutiquement acceptable par conséquent, l'agent de décorporation de l'actinide comprenant un analogue de la desferrithiocine hexacoordonnée capable de chélater un actinide in vivo et un procédé pour enlever un actinide d'un tissue d'un mammifère humain ou non humain.

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