C - Chemistry – Metallurgy – 08 – F
Patent
C - Chemistry, Metallurgy
08
F
C08F 20/58 (2006.01) A61F 13/00 (2006.01) A61K 8/02 (2006.01) A61K 8/81 (2006.01) A61K 47/32 (2006.01) A61L 15/24 (2006.01) A61L 15/60 (2006.01) A61L 26/00 (2006.01) A61Q 19/00 (2006.01) C08F 2/48 (2006.01)
Patent
CA 2412811
The present invention provides a process for the manufacture of a high water content (greater than about 40 % by weight of water) cross-linked hydrogel composition which has an acceptable non-greasy "feel", sufficient structural integrity and low brittleness, as well as good processing properties. In the process, a photopolymerisable monomer is photopolymerised, in the presence of water, low levels of a multifunctional photopolymerisable cross-linking agent (less than about 0.5 % by weight of the total polymerisation reaction mixture) and low levels of a photoinitiator (between about 0.002 % and about 0.05 % by weight of the total polymerisation reaction mixture).
La présente invention concerne un procédé de production d'une composition d'hydrogel réticulé à teneur en eau élevée (supérieure à environ 40 % en poids), de texture non grasse, d'intégrité structurale suffisante, de faible fragilité et à bonnes propriétés de traitement. Selon ledit procédé, un monomère photopolymérisable est photopolymérisé, en présence d'eau, d'un agent de réticulation photopolymérisable multifonction (teneur inférieure à environ 0,5 % en poids du mélange réactionnel de polymérisation total) et d'un photoamorceur (teneur comprise entre environ 0,002 % et environ 0,05 % en poids du mélange réactionnel de polymérisation total).
Donnelly Michael Joseph
Munro Hugh Semple
Page Alison
First Water Limited
Gowling Lafleur Henderson Llp
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