C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/42 (2006.01) A61K 39/395 (2006.01) A61P 37/08 (2006.01)
Patent
CA 2736511
The present invention relates to immunoglobulins that bind IgE and Fc.gamma.Rllb with high affinity, said compositions comprising said immunoglobulins being capable of inhibiting cells that express membrane-anchored IgE. Such compositions are useful for treating IgE-mediated disorders, including allergies and asthma.
La présente invention concerne des immunoglobulines qui lient les IgE et Fc?Rllb avec une affinité élevée, lesdites compositions contenant lesdites immunoglobulines capables d'inhiber les cellules qui expriment des IgE ancrées à la membrane. Ces compositions sont utiles pour traiter les affections médiées par les IgE, notamment des allergies et l'asthme.
Chu Seung Y.
Desjarlais John R.
Horton Holly M.
Smart & Biggar
Xencor Inc.
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