Sterile fluid filtration cartridge and method for using same

B - Operations – Transporting – 01 – D

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B01D 63/04 (2006.01) A61L 2/00 (2006.01) A61L 2/02 (2006.01) A61M 5/165 (2006.01) B01D 61/14 (2006.01) B01D 61/18 (2006.01) A61M 1/34 (2006.01)

Patent

CA 2395697

A filtration assembly (1) is presented which removes bacteria and endotoxin from a solution that a sterile fluid is produced. The sterile fluid is suitable for direct online infusion to a patient from a device, such as a dialysis machine. The filtration assembly is constructed so that two separate compartments (2) exist, resulting in redundant filtration of the fluid prior to infusion. Each compartment holds a filter which preferably consists or a longitudinal bundle of semipermeable hollow fibers (14). The filter is sized so that it creates a separate area within the compartment for filtrate and infusate flow. This redundant filtration produces a lower risk of creating a pyrogenic or septic condition in the patient due to filter failure.

L'invention concerne un ensemble de filtration (1) qui élimine les bactéries et les endotoxines d'une solution afin de produire un liquide stérile. Le liquide stérile convient pour une infusion directe en ligne d'un appareil, tel qu'une machine de dialyse, à un patient. L'ensemble de filtration présente deux compartiments de filtration (2) séparés, ce qui permet une filtration redondante du liquide avant infusion. Chaque compartiment comprend un filtre constitué, de préférence, d'un faisceau longitudinal de fibres creuses semi-perméables (14). Le filtre est dimensionné de manière à créer, à l'intérieur du compartiment, une zone séparée assurant l'écoulement du filtrat et de la solution intraveineuse. Cette filtration redondante réduit le risque de créer chez le patient un état pyrogène ou septique dû à une défaillance du filtre.

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