Modulating phosphatase activity in cardiac cells

Details Modulating phosphatase activity in cardiac cells Modulating phosphatase activity in cardiac cells

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61P 9/00 (2006.01) C12N 7/00 (2006.01) C12N 15/12 (2006.01) C12N 15/86 (2006.01) C12N 9/16 (2006.01)

Patent

CA 2579519

Expression of a phosphatase inhibitor in heart cells can be used to treat cardiac disorders, e.g., heart failure. Decreasing phosphatase activity can improve .beta.-adrenergic responsiveness.

L'expression d'un inhibiteur de la phosphatase dans les cellules cardiaques peut être utilisée pour le traitement de maladies cardiaques, telles que par exemple l'insuffisance cardiaque. La réduction de l'activité de la phosphatase peut améliorer la réactivité .beta.-adrénergique.

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