A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/49 (2006.01) A61K 9/72 (2006.01) A61K 33/00 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2685446
The present invention relates to a pharmaceutical composition comprising at least one thrombolytic agent (A), such as the human recombinant form of tissue-type plasminogen activator (rt-PA), and at least one gas (B) selected from the group consisting of nitrous oxide, argon, xenon, helium, neon, and mixtures thereof, as a combined composition for simultaneous, separate or sequential use for treating ischemia. The present invention also relates to the use of at least one thrombolytic agent (A), such as the human recombinant form of tissue-type plasminogen activator (rt-PA), and at least one gas (B) selected from the group consisting of nitrous oxide, argon, xenon, helium, neon, and mixtures thereof, for the preparation of a combined pharmaceutical composition for treating ischemia.
L'invention concerne une composition pharmaceutique comprenant au moins un agent thrombolytique (A), par exemple la forme recombinante humaine d'activateur de plasminogène de type tissulaire (rt-PA), et au moins un gaz (B) choisi dans le groupe formé d'oxyde nitrique, d'argon, de xénon, d'hélium, de néon et de mélanges de ceux-ci, comme composition combinée pour utilisation simultanée, séparée ou séquentielle en vue de traiter l'ischémie. L'invention concerne également l'utilisation d'au moins un agent thrombolytique (A), par exemple la forme recombinante d'activateur plasminogène de type tissulaire (rt-PA), et au moins un gaz (B) choisi dans le groupe formé d'oxyde nitrique, d'argon, de xénon, d'hélium, de néon et de mélanges de ceux-ci, en vue de préparer une composition pharmaceutique combinée destinée au traitement de l'ischémie.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Nnoxe Pharmaceutiques Inc.
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