Combination therapy comprising ribavirin and interferon...

A - Human Necessities – 61 – K

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A61K 38/21 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2331823

Use of ribavirin and interferon alpha to prepare pharmaceutical compositions for treating antiviral treatment naive patient having chronic hepatitis C infection to eradicate detectable HCV-RNA involving a combination therapy using a therapeutically effective amount of ribavirin and a therapeutically effective amount of interferon alpha for a time period of from 20 up to 50 weeks are disclosed.

L'invention porte sur l'utilisation de la ribavirine et de l'interféron alpha dans la préparation de compositions pharmaceutiques destinées à traiter des novices aux essais cliniques par administration d'agents antiviraux, ces novices étant atteints de l'hépatite C chronique, pour éradiquer l'ARN du virus de l'hépatite C détectable. L'invention porte également sur une thérapeutique associée utilisant une quantité thérapeutiquement efficace de ribavirine et d'interféron alpha sur une durée allant de 20 à 50 semaines.

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