C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/68 (2006.01) A61K 31/341 (2006.01) A61P 29/02 (2006.01)
Patent
CA 2448038
The invention relates to substituted C-furan-2-yl-methylamine and C-thiophen-2- yl-methylamine derivatives of general formula (I), a method for the production thereof, medicaments and pharmaceutical compositions containing said derivatives, and the use of the same for producing analgesics, for producing a local anaesthetic, an anti--arrhythmic agent, an anti-emetic agent, a nootropic agent and/or a medicament for the treatment and/or the prophylaxis of cardiovascular diseases, urinary incontinence, diarrhoea, pruritus and/or inflammations, and/or a medicament for treating depression, and/or the misuse of alcohol and/or drugs and/or medicines, and/or a medicament for increasing vigilance.
La présente invention concerne des dérivés substitués de C-furan-2-yl-méthylamine et C-thiophén-2-yl-méthylamine de formule générale (I), un procédé permettant leur préparation, des médicaments et compositions pharmaceutiques les contenant, ainsi que leur utilisation pour produire des analgésiques, pour produire un anesthésique local, un agent anti-arrythmie, un agent antiémétique, un agent nootropique et/ou un médicament servant à traiter et/ou à prévenir les maladies cardio-vasculaires, l'incontinence urinaire, la diarrhée, le prurit et/ou les inflammations, et/ou un médicament servant à traiter les dépressions et/ou la dépendance à l'alcool et/ou aux drogues et/ou aux médicaments, et/ou un médicament servant à augmenter la vigilance.
Przewosny Michael
Sundermann Corinna
Fetherstonhaugh & Co.
Gruenenthal Gmbh
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