N-¬(r)-1-{3-(4-piperidyl)propionyl}-3-piperidylcarbonyl|-2(s...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/60 (2006.01) A61K 31/455 (2006.01)

Patent

CA 2248809

This invention relates to .beta.-alanine derivative represented by formula (I), which is glycoprotein IIB/IIIa antagonist, inhibitor of blood platelets aggregation and inhibitor of the binding of fibrinogen to blood platelets, to processes for the preparation thereof, to a pharmaceutical composition comprising the same and to a method for the prevention and/or treatment of diseases indicated in the specification to a human being or an animal.

Dérivé de .beta.-alanine représenté par la formule (I). Ce dérivé est un antagoniste de la glycoprotéine IIB/IIIa, un inhibiteur de l'agrégation des plaquettes sanguines et un inhibiteur de la liaison du fibrinogène aux plaquettes sanguines. L'invention porte également sur des procédés d'élaboration de ce dérivé, sur une composition pharmaceutique le renfermant et sur une méthode de prévention et/ou de traitement de maladies indiquées dans la description de l'invention, chez l'être humain et l'animal.

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