Heteroaryl coumarins as inhibitors of leukotriene biosynthesis

Details Heteroaryl coumarins as inhibitors of leukotriene biosynthesis Heteroaryl coumarins as inhibitors of leukotriene biosynthesis

C - Chemistry, Metallurgy

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C07D 493/08 (2006.01) A61K 31/37 (2006.01) A61K 45/06 (2006.01) C07D 311/16 (2006.01) C07D 407/12 (2006.01) C07D 407/14 (2006.01) C07D 409/14 (2006.01) C07D 411/12 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 491/048 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2125824

Compounds having the formula I: (see formula I) are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.

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