Heteroaryl benzamide derivatives for use as glk activators...

Details Heteroaryl benzamide derivatives for use as glk activators... Heteroaryl benzamide derivatives for use as glk activators...

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) A61K 31/44 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2614746

Compounds of formula (I) (see formula I) wherein R1, HET-1 and HET-2 are as described in the specification, and their salts and pro-drugs, are activators of glucokinase (GLK) and are thereby useful in the treatment of, for example, type 2 diabetes. Processes for preparing compounds of formula (I) are also described.

La présente invention concerne des composés de formule (I), R1, HET-1 et HET-2 étant tels que définis dans la description, ainsi que leurs sels et promédicaments, qui sont des activateurs de la glucokinase (GLK) et sont par conséquent utiles dans le traitement du diabète de type 2, par exemple. L~invention concerne également des procédés de préparation des composés de formule (I).

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