Selecting patients for therapy with a her inhibitor

Details Selecting patients for therapy with a her inhibitor Selecting patients for therapy with a her inhibitor

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2587519

A method for selecting patients for therapy with a HER inhibitor, such as pertuzumab, based on gene expression analysis is described. A method for assessing HER phosphorylation or activation in a biological sample via gene expression analysis is also described.

L'invention concerne un procédé pour sélectionner des patients pour une thérapie avec un inhibiteur de HER, tel que le pertuzumab, sur la base d'une analyse de l'expression génique. La présente invention porte également sur un procédé pour évaluer une phosphorylation ou une activation HER dans un échantillon biologique par analyse de l'expression génique.

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