Non-protein stabilized clostridial toxin pharmaceutical...

Details Non-protein stabilized clostridial toxin pharmaceutical... Non-protein stabilized clostridial toxin pharmaceutical...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 38/48 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2602926

A Clostridial toxin pharmaceutical composition comprising a Clostridial toxin, such as a botulinum toxin, wherein the Clostridial toxin present in the pharmaceutical composition is stabilized by a non-protein excipient such as a polyvinylpyrrolidone, a disaccharides, a trisaccharide, a polysaccharide, an alcohol, a metal, an amino acid, a surfactant and/or a polyethylene glycol.

La présente invention porte sur une préparation pharmaceutique de toxine clostridiale qui comprend une toxine clostridiale, telle qu'une toxine botulique, ladite toxine clostridiale présente dans la préparation pharmaceutique étant stabilisée par un excipient non protéinique tel qu'une polyvinylpyrrolidone, un disaccharide, un trisaccharide, un polysaccharide, un alcool, un métal, un acide aminé, un tensioactif et/ou un polyéthylène glycol.

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