Transdermal patch for delivering volatile liquid drugs

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/70 (2006.01) A61K 31/13 (2006.01) A61K 31/131 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/465 (2006.01) C07C 211/27 (2006.01) C07C 211/36 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2380391

A transdermal patch for administering a volatile liquid drug, such as nicotine, transdermally to a patient comprising a four-layer laminated composite of: a top drug impermeable backing layer; a pressure sensitive silicone adhesive layer containing the drug; a pressure sensitive acrylic adhesive layer also containing the drug; and a removable siliconized release liner layer. Also disclosed is a method for treating a person for nicotine dependence and particularly for treating a woman for nicotine dependence.

L'invention concerne un timbre transdermique servant à administrer par voie transdermique un médicament liquide volatile, tel que de la nicotine, à un patient. Le timbre transdermique comprend un matériau composite multicouche constitué de quatre couches: une couche supérieure de soutien imperméable au médicament, une couche adhésive siliconée sensible à la pression, une couche adhésive acrylique sensible à la pression et contenant le médicament, et une couche intérieure siliconée anti-adhérente amovible. L'invention concerne en outre un procédé qui permet de traiter une personne, et notamment une femme, de la dépendance à la nicotine.

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