Novel methods for the in-vitro identification, isolation and...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/077 (2010.01) A61K 35/12 (2006.01) C12Q 1/04 (2006.01)

Patent

CA 2584256

A simplified and inexpensive method for the in-vitro identification, isolation and culture of human vasculogenic progenitor cells is provided. The method and the progenitor cells provided herein can be used for in-vitro vascular engineering, treatment of congenital and acquired vascular and hematological abnormalities, for evaluation and development of drugs affecting vasculo- and angiogenic processes, and for further investigation into tissue differentiation and development.

L'invention porte sur un procédé simplifié et peu coûteux d'identification, d'isolation et de mise en culture in vitro de cellules progénitrices vasculogéniques humaines. Le procédé et les cellules progénitrices peuvent être utilisés dans le développement vasculaire in vitro, le traitement d'anomalies congénitales et hématologiques et de maladies vasculaires acquises, dans l'évaluation et le développement de médicaments affectant des processus vasculaires et angiogéniques, et également dans l'investigation de la différenciation et du développement tissulaire.

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