C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2550192
The invention relates to nucleic acid probes and to broad-range primers that are useful in the identification of bacte-rial species and the diagnosis of bacterial infections. Es-pecially, the invention relates to specific nucleic acid probes that originate from hyper-variable regions situated near the conserved sequences of the gene for RNA poly-merase beta subunit, rpoB (DNA directed RNA poly-merase subunit B) of infection-causing bacteria. The in- vention also relates to broad-range primers originating from the conserved regions of rpoB genes. In addition, the invention relates to the use of these nucleic acid probes and broad-range primers in the diagnosis of bacterial in- fections as well as to diagnostic methods in which these nucleic acid probes and broad-range primers are used.
L'invention concerne des sondes d'acide nucléique et des amorces à large spectre utiles pour identifier des espèces bactériennes et diagnostiquer des infections bactériennes. Plus spécifiquement, l'invention concerne des sondes d'acide nucléique spécifiques qui proviennent de régions hyperviariables se situant à proximité de séquences conservées du gène de sous-unité bêta pour l'ARN polymérase, rpoB (sous-unité B d'ARN polymérase dirigée par ADN) de bactéries provoquant des infections. Cette invention concerne également des amorces à large spectre qui proviennent des régions conservées de gènes rpoB. En outre, l'invention concerne l'utilisation de ces sondes d'acide nucléique et amorces à large spectre dans le diagnostic d'infections bactériennes ainsi que pour des procédés diagnostiques dans lesquels ces sondes d'acide nucléique et amorces à large spectre sont utilisées.
Jalava Jari
Nikkari Simo
Palgi Jaan
Freedman Gordon
Mobidiag Oy
LandOfFree
Nucleic acid probes and broad-range primers from regions in... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleic acid probes and broad-range primers from regions in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid probes and broad-range primers from regions in... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1898415