Imidazo[1,2-a]pyridine compounds, compositions, uses and...

Details Imidazo[1,2-a]pyridine compounds, compositions, uses and... Imidazo[1,2-a]pyridine compounds, compositions, uses and...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/44 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01)

Patent

CA 2585315

The present invention relates to novel imidazo[1,2- a]pyridine compounds of general formula (I) as well as pharmaceutically acceptable salts thereof; wherein R1, R2, R3 and R4 are as defined in the claims. The compounds have specific affinity for GABAA receptor and are therefore useful in the treatment and prevention of diseases modulated by .alpha.1- and .alpha.2-GABAA receptors.

La présente invention a pour objet de nouveaux dérivés d'imidazo[1,2-a]pyridine de formule générale (I), ainsi que des sels de qualité pharmaceutique desdits dérivés, où R1, R2, R3 et R4 sont tels que définis dans les revendications. Lesdits dérivés ont une affinité spécifique pour le récepteur GABAA, et peuvent donc être employés dans le traitement prophylactique et thérapeutique de maladies régulées par les récepteurs GABAA .alpha.1 et .alpha.2.

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