New polynucleotides and polypeptides of the erythropoietin gene

Details New polynucleotides and polypeptides of the erythropoietin gene New polynucleotides and polypeptides of the erythropoietin gene

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 1/14 (2006.01) C07K 14/505 (2006.01) C07K 16/22 (2006.01) C12N 5/10 (2006.01) C12N 15/10 (2006.01) C12N 15/85 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2443373

The present invention relates to new polynucleotides deriving from the nucleotide sequence of the EPO gene and comprising new SNPs, new polypeptides derived from the natural EPO protein and comprising at least one mutation caused by the SNPs of the invention as well as their therapeutic uses.

L'invention concerne des polynucléotides issus de la séquence nucléotidique du gène de l'EPO et comprenant de nouveaux polymorphismes d'un nucléotide simple (PNS). L'invention concerne également des polypeptides issus de la protéine de l'EPO naturelle et comprenant au moins une mutation résultant des PNS, y compris les utilisations thérapeutiques correspondantes.

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