Monoclonal antibodies specific for tcf-ii

Details Monoclonal antibodies specific for tcf-ii Monoclonal antibodies specific for tcf-ii

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) C07K 1/22 (2006.01) C07K 14/475 (2006.01) C07K 14/52 (2006.01) C07K 16/22 (2006.01) C07K 16/24 (2006.01) C12N 5/12 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2145005

This invention relates to a monoclonal antibody having affinity to human TCF-II without any affinity to HGF and determination or purification method of TCF- II using the antibody. The monoclonal antibody can be obtained by adding a blocking solution containing a surface active agent to the culture medium containing monoclonal antibody to block antibodies other than said monoclonal antibody, followed by reaction with a solid phase antigen, TCF- II. Human TCF- II can be selectively and effectively purified or determined without any influence of the presence of HGF by using the antibody.

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