Indole derivatives as serotonin reuptake inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 405/12 (2006.01) A61K 31/4045 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2529299

Disclosed are compounds of formula (I), the use thereof for producing a medicament utilized for treating diseases related to the serotonin receptor and/or serotonin reuptake, especially for producing a medicament utilized as an anxiolytic, antidepressant, neuroleptic, and/or antihypertensive and/or for positively influencing obsessive-compulsive behavior (OCD), sleeping disorders, tardive dyskinesia, learning disorders, age-related memory defects, eating disorders such as bulimia, and/or sexual dysfunctions. The inventive compounds bond to the 5-HT1A receptor.

L'invention concerne des composés de formule (I), leur utilisation pour produire un médicament servant à traiter des maladies en rapport avec le récepteur de la sérotonine et/ou la recapture de la sérotonine, notamment pour produire un médicament servant d'anxiolytique, d'antidépresseur, de neuroleptique et/ou d'anti-hypertonique, et/ou servant à influencer positivement des troubles obsessionnels compulsifs, des troubles du sommeil, des dyskinésies tardives, des troubles d'apprentissage, des troubles de la mémoire liés à l'âge, des troubles de l'alimentation comme la boulimie et/ou des troubles de la fonction sexuelle. Les composés (I) se lient au récepteur 5-HT¿1A?.

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