Polymorphs of pyrrole substituted 2-indolinone protein...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/14 (2006.01) A61K 31/404 (2006.01)

Patent

CA 2516900

The present invention relates to polymorphs of the 3-pyrrole substituted 2- indolinone compound 5-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-pyrrolidin-1-yl-ethyl)-amide.

L'invention concerne des polymorphes de composé 2-indolinone à substitution de pyrrole du type 5-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidèneméthyle)-2,4-diméthyle-1H-pyrrole-3-acide caboxylique (2-pyrrolidine-1-yl-éthyle)-amide.

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