Use of growth differentiation factor-9 (gdf-9) as a...

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A61K 38/18 (2006.01) A61K 31/185 (2006.01) A61K 39/00 (2006.01) C07K 14/475 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2306452

Growth differentiation factor-9 (GDF-9) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed is a method for inhibiting oocyte maturation using GDF-9 inhibitors or by inducing an immune response to GDF-9 polypeptide or fragments thereof.

L'invention se rapporte au facteur-9 de différentiation de la croissance (GDF-9) ainsi qu'à sa séquence polynucléotidique et à sa séquence d'acides aminés. L'invention concerne également un procédé pour freiner la maturation des oocytes au moyen d'inhibiteurs du GDF-9 ou par l'induction d'une réponse immunitaire au polypeptide du GDF-9 ou à ses fragments.

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