C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/58 (2006.01) A61K 31/451 (2006.01) A61P 3/04 (2006.01) C07D 211/34 (2006.01) C07D 211/52 (2006.01) C07D 211/96 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 409/04 (2006.01) C07D 409/06 (2006.01) C07D 409/14 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2467857
The present invention discloses compounds of formula I, which are novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.
L'invention concerne des composés représentés par la formule (I) qui sont de nouveaux antagonistes de l'hormone de concentration de la mélanine (MCH), ainsi que des procédés de préparation de ces composés. Dans un autre mode de réalisation, l'invention concerne des compositions pharmaceutiques qui contiennent des antagonistes de la MCH, ainsi que des méthodes d'utilisation de ces derniers pour traiter l'obésité, les troubles métaboliques, les troubles de l'alimentation tels que l'hyperphagie, et le diabète.
Burnett Duane A.
Wu Wen-Lian
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
Schering Corporation
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