Sulfonated xanthene derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 311/82 (2006.01) C07D 405/12 (2006.01) C07D 491/14 (2006.01) C07D 491/22 (2006.01) C07H 3/06 (2006.01) C07H 19/04 (2006.01) C07H 21/00 (2006.01) C07K 14/415 (2006.01) C09B 11/08 (2006.01) C09B 11/24 (2006.01) G01N 1/30 (2006.01)

Patent

CA 2272403

The present invention describes xanthene dyes, including rhodamines, rhodols and fluoresceins that are substituted one or more times by a sulfonic acid or a salt of a sulfonic acid. The dyes of the invention, including chemically reactive dyes and dye-conjugates are useful as fluorescent probes, particularly in biological samples.

Cette invention concerne des colorants xanthènes, comprenant des rhodamines, des génols et des fluorescéines qui sont substitués une ou plusieurs fois par un acide sulfonique ou par un sel d'un acide sulfonique. Les colorants de cette invention, y compris les colorants et les conjugués de colorants chimiquement réactifs sont utiles en tant que sondes fluorescentes, plus particulièrement dans des prélèvements biologiques.

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