Spirocyclic oxytocin antagonists

Details Spirocyclic oxytocin antagonists Spirocyclic oxytocin antagonists

C - Chemistry, Metallurgy

07

D

167/232, 167/233

C07D 221/20 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) C07D 209/96 (2006.01) C07D 401/02 (2006.01) C07D 405/12 (2006.01) C07D 471/10 (2006.01) C07D 487/10 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2037287

30/CMC5 17895 TITLE OF THE INVENTION SPIROCYCLIC OXYTOCIN ANTAGONISTS ABSTRACT OF THE INVENTION Disclosed are spirocyclic compounds of the formula: Image (I) The compounds of formula I are oxytocin antagonists useful in the treatment of preterm labor and dysmenorrhea, and for the stoppage of labor preporatory to Caesarian delivery. Also disclosed are pharmaceutical compositions containing these compounds as well as methods for preparing the compounds.

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