New carbohydrate-based anti-inflammatory agents

Details New carbohydrate-based anti-inflammatory agents New carbohydrate-based anti-inflammatory agents

C - Chemistry, Metallurgy

07

K

C07K 2/00 (2006.01) A61K 31/715 (2006.01) A61K 38/02 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07H 5/06 (2006.01) C07H 13/04 (2006.01) C07H 15/04 (2006.01) C07H 15/10 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2100600

-63- ABSTRACT OF THE DISCLOSURE Ligands that bind to human selectin receptors are disclosed. The ligands are formulated with excipient carriers to form compositions which are administered to treated condition such as inflammation. The ligands have the structural formula III (III) Image or molecules which have hydrogen bond donor groups equivalent to the circled groups with respect to their ability to form hydrogen bonds with a selectin under physiological conditions.

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