Therapeutic use of a growth factor, metrnl

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/18 (2006.01) C12N 5/071 (2010.01) A61K 31/7088 (2006.01) A61K 35/12 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61L 27/28 (2006.01) A61L 27/38 (2006.01) C07K 14/475 (2006.01) C12N 7/00 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2730710

The present invention relates to the field of therapeutic use of proteins, genes and cells, in particular to the therapy based on the biological function of a secreted therapeutic protein, METRNL, in particular for the treatment of disorders of the ner-vous system. METRNL is a Nerve Survival and Growth factor with neuroprotective and/or neurogenesis effects.

La présente invention concerne le domaine de l'utilisation thérapeutique de protéines, de gènes et de cellules. L'invention porte plus particulièrement sur la thérapie basée sur la fonction biologique d'une protéine thérapeutique secrétée, METRNL, notamment dans le traitement de troubles du système nerveux. METRNL est un facteur de croissance et de survie des cellules nerveuses qui présente des effets neuroprotecteurs et/ou de neurogenèse.

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