Long lasting drug formulations

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/20 (2006.01) A61K 38/17 (2006.01) A61K 38/21 (2006.01) A61K 38/22 (2006.01) A61K 48/00 (2006.01) A61P 7/06 (2006.01) C12N 15/18 (2006.01) C12N 15/67 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2664318

The present invention is directed to long-lasting therapeutic formulations and their methods of use wherein the formulation comprises a genetically modified micro-organ that comprises a vector which comprises a nucleic acid sequence operably linked to one or more regulatory sequences, wherein the nucleic acid sequence encodes a therapeutic polypeptide, such as erythropoietin or interferon alpha.

La présente invention concerne des formulations thérapeutiques de longue durée et leurs procédés d'utilisation, la formulation comprenant un micro-organe génétiquement modifié qui comprend un vecteur qui comprend une séquence d'acide nucléique liée de façon fonctionnelle à une ou plusieurs séquences régulatrices, la séquence d'acide nucléique codant pour un polypeptide thérapeutique, tel que l'érythropoïétine ou un interféron alpha.

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