C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C40B 50/02 (2006.01)
Patent
CA 2577126
The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic composition and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
La présente invention concerne de nouvelles séquences à utiliser dans la détection, le diagnostic et le traitement de cancers, en particulier de lymphomes. Cette invention concerne des séquences polynucléotidiques associées au cancer, dont l'expression est associée au cancer. Ladite invention concerne également des polypeptides associés au cancer, présents à la surface de cellules et comportant de nouvelles cibles thérapeutiques contre le cancer. La présente invention concerne en outre des compositions de diagnostic et des méthodes de détection du cancer. Cette invention se rapporte également à des anticorps monoclonaux et polyclonaux spécifiques des polypeptides associés au cancer, des outils de diagnostic et des compositions thérapeutiques ainsi que des méthodes de dépistage, de prévention et de traitement du cancer.
Fattaey Ali R.
Lai Albert
Malandro Marc S.
Morris David W.
Tse Christin
Borden Ladner Gervais Llp
Sagres Discovery Inc.
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