Method of using neurotrophic sulfonamide compounds

Details Method of using neurotrophic sulfonamide compounds Method of using neurotrophic sulfonamide compounds

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/18 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01)

Patent

CA 2280742

This invention relates to a method of using neurotrophic low molecular weight, small molecule sulfonamide compounds having an affinity for FKBP-type immunophilins, as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.

Cette invention concerne un procédé d'utilisation de composés sulfamides neurotrophiques, à petites molécules et faible poids moléculaire qui ont une affinité pour les immunophillines de type FKBP et qui sont utiles comme inhibiteurs de l'activité enzymatique associée à des protéines immunophillines, notamment l'activité enzymatique de l'isomérase peptidyle-propyle ou la rotamase.

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