Method for diagnosing a disorder by determining expression...

Details Method for diagnosing a disorder by determining expression... Method for diagnosing a disorder by determining expression...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 35/18 (2006.01) A61K 39/00 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2167692

A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as GAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described.

L'invention concerne une nouvelle famille de précurseurs des antigènes de rejet des tumeurs et les molécules d'acide nucléique codant pour ces précurseurs. On les appelle respectivement les précurseurs GAGE des antigènes de rejet des tumeurs et les molécules codantes GAGE. Sont décrites diverses applications diagnostiques et thérapeutiques des séquences de codage et des antigènes de rejet des tumeurs, ainsi que leurs molécules-précurseurs.

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