Markers for lxr activation

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2524675

The present invention relates to surrogate markers for LXR activation, and methods of diagnosing a disease linked to LXR activation, methods of monitoring the treatment of patients suffering from a disease linked to LXR activation, and methods of identifying compounds which modulate LXR activity.

La présente invention concerne des marqueurs de substitution permettant l'activation du récepteur LXR, et des procédés pour diagnostiquer une maladie liée à l'activation du récepteur LXR. L'invention concerne aussi des procédés pour suivre le traitement de patients atteints d'une maladie liée à l'activation du récepteur LXR, et des procédés pour identifier des composés qui modulent l'activité du récepteur LXR.

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