The use of halofuginone and related compounds for the...

A - Human Necessities – 61 – K

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A61K 31/517 (2006.01) A61P 13/02 (2006.01)

Patent

CA 2384331

A promotor of wound healing and an inhibitor of formation of a urethral stricture, particularly following surgical intervention or infection in the area. Specifically, the most preferred compound of the present invention, Halofuginone, can be used to prevent collagen deposition from occurring within the lumen of the urethra after such trauma, thereby inhibiting urethral stricture formation. Halofuginone, and related compounds, are also useful for the promotion of wound healing after trauma, for example after surgery.

L'invention concerne un promoteur de cicatrisation de blessures et un inhibiteur de formation de rétrécissement de l'urètre, notamment suite à une intervention chirurgicale ou une infection de la zone. De manière plus spécifique, l'halofuginone composé idéal de l'invention, peut être utilisé pour empêcher la formation d'un dépôt de collagène dans la lumière de l'urètre après un traumatisme, ce qui évite la formation d'un rétrécissement de l'urètre. L'halofuginone et les composés associés sont utiles pour la promotion de la cicatrisation d'une blessure après un traumatisme, par exemple après une intervention chirurgicale.

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