G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01)
Patent
CA 2658665
The present invention relates to an assay for determining the implantation potential of a plurality of embryos each obtained or to be obtained by assisted fertilisation of an oocyte of a female subject, comprising measuring the levels of granulocyte-colony stimulating factor (G-CSF) in the follicular fluid (FF) present in the follicle from which each oocyte is derived, and determining the implantation potential of each embryo from the level of measured FF G-CSF. It also relates to a kit for carrying out the assay. It further relates to a method for assisted fertilisation.
La présente invention concerne un dosage permettant de déterminer le potentiel d'implantation d'une pluralité d'embryons, chacun obtenu ou devant être obtenu par fécondation assistée d'un ovocyte d'un sujet femelle, consistant à mesurer les niveaux de facteur stimulant les colonies de granulocytes (G-CSF) dans le liquide folliculaire (FF) présent dans le follicule à partir duquel chaque ovocyte est issu, et à déterminer le potentiel d'implantation de chaque embryon à partir du niveau de G-SCF de FF mesuré. L'invention concerne également une trousse pour la mise en oeuvre du dosage. L'invention concerne en outre une méthode de fécondation assistée.
Ledee Nathalie
Piccinni Marie-Pierre
Femalon S.a.
Mithra Pharmaceuticals Nv/sa
Smart & Biggar
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