Inhibiting agent against platelet-derived growth factor...

A - Human Necessities – 61 – K

Patent

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A61K 31/365 (2006.01)

Patent

CA 2277564

Disclosed are an inhibiting agent against platelet-derived growth factor increase, an arteriosclerosis preventive and therapeutic agent, and an arterial intimal thickening inhibiting agent, comprising as an active ingredient a diterpene selected from a compound represented by formula (I), (see image I) a compound represented by formula (II), (see image II) wherein X1, X2 and X3 independently represent a hydroxyl group or a hydrogen atom, and derivatives thereof, utilizing an ability of inhibiting an increase of platelet-derived growth factor as an index.

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