Tetrahydroquinoline derivatives for treating post-traumatic...

A - Human Necessities – 61 – K

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Details

A61K 31/472 (2006.01) A61K 31/4725 (2006.01) A61P 25/00 (2006.01) A61P 25/22 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2699504

The invention relates to the use of tetrahydroquinoline derivatives of formula I wherein R1 and R2 each independently represent (C1-C4 4)alkoxy, R3 represents aryl-(C1-C4)alkyl or heteroaryl-(C1-C4)alkyl, and R represents hydrogen or (C1-C4)alkyl, or of pharmaceutically acceptable salts thereof, for the preparation of a medicament for preventing or treating post-traumatic stress disorders.

L'invention concerne l'utilisation de dérivés de tétrahydroquinoléine représentés par la formule (I), R1 et R2 représentant chacun indépendamment un groupe alcoxy en C1-C4, R3 représentant un groupe arylalkyle en C1-C4 ou hétéroarylalkyle en C1-C4, et R4 représentant un atome d'hydrogène ou un groupe alkyle en C1-C4, ou de sels pharmaceutiquement acceptables de ces dérivés, pour la préparation d'un médicament destiné à prévenir ou traiter des troubles de stress post-traumatique.

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