Marker for individuals susceptible to alcoholism

Details Marker for individuals susceptible to alcoholism Marker for individuals susceptible to alcoholism

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C07K 16/40 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2198863

The present invention relates to methods for diagnosis of susceptibility to alcoholism or the pathological effects of alcoholism based on detection of a genetic marker in an individual. The present invention is directed generally to methods and associated compositions and kits for detecting the presence of arylsulfatase A (ASA) pseudodeficiency (PD) mutations in humans. Detection of these mutations has been surprisingly found to be a strong indicator for susceptibility to alcoholism and/or susceptibility to alcohol's pathological effects, as well as an important marker in evaluating the likelihood of metachromatic leukodystrophy (MLD).

L'invention concerne des procédés de diagnostic de la prédisposition à l'alcoolisme ou aux effets pathologiques de l'alcoolisme, qui consistent à détecter un marqueur génétique chez un individu. L'invention concerne, de façon générale, des procédés, des compositions associées et des kits servant à détecter la présence de mutations de pseudodéficience (PD) d'arylsulfatase A (ASA) chez l'homme. La détection de ces mutations s'est avérée constituer un indicateur puissant de la prédisposition à l'alcoolisme et/ou aux effets pathologiques de l'alcool, ainsi qu'un marqueur important d'évaluation de la présence éventuelle de leucodystrophie métachromatique (MLD).

Affiliated with

Also associated with

Rating

Marker for individuals susceptible to alcoholism does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Marker for individuals susceptible to alcoholism, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Marker for individuals susceptible to alcoholism will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1905621