Medicaments and proteins based on tgf-beta monomers for the...

A - Human Necessities – 61 – K

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A61K 38/18 (2006.01) A61P 17/02 (2006.01)

Patent

CA 2645345

There is provided the use of monomeric TGF-.beta.s, or there fragments or derivatives, as medicaments. These medicaments preferably comprise monomeric TGF-.beta.3, or fragments or derivatives thereof. The medicaments provided may be used in the acceleration of wounding and/or the inhibition of scarring, in the promotion of epithelial regeneration, or in the prevention and/or treatment of fibrotic disorders.

L'invention concerne l'utilisation de TGF-.beta. monomères, ou de leurs fragments ou dérivés, comme médicaments. De préférence, ces médicaments contiennent des TGF-.beta. monomères, ou des fragments ou dérivés de ceux-ci. Ces médicaments peuvent servir à: accélérer la guérison des plaies et/ou empêcher la cicatrisation; favoriser la régénération épithéliale; et à prévenir et/ou traiter les troubles fibreux.

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